Drew Brees, QB, New Orleans Saints (Purdue): Threw for five touchdowns on 18 of 23 passing for 371 yards in the Saints' 38-17 win over New England on Monday night.
Kyle Orton, QB, Denver (Purdue): Completed 18 of 28 passes for 245 yards and a touchdown pass in the Broncos' 26-6 win over the New York Giants on Thursday night.
Laurence Maroney, RB, New England (Minnesota): Rushed for 64 yards on 15 caries and scored two touchdowns in the Patriots' 38-17 loss to New Orleans on Monday night.
Pierre Thomas, RB, New Orleans (Illinois): Rushed for 64 yards on 11 caries and caught a touchdown pass in the Saints' 38-17 win over New England on Monday night.
Santonio Holmes, WR, Pittsburgh (Ohio State): Caught six passes for 74 yards and a touchdown reception in the Steelers' 20-17 loss to Baltimore on Sunday night.
Chris Chambers, WR, Kansas City (Wisconsin): Caught seven passes for 70 yards with a touchdown catch in the Chiefs' 43-14 loss to San Diego.
Derrick Mason, WR, Baltimore (Michigan State): Made seven catches for 62 yards with a touchdown grab in the Ravens' 20-17 win over Pittsburgh on Sunday night.
Brian Hartline, WR, Miami (Ohio State): Recorded three catches for 31 yards with a touchdown reception in the Dolphins' 31-14 loss to Buffalo.
Dallas Clark, TE, Indianapolis (Iowa): Made nine catches for 63 yards and a touchdown in the Colts' 35-27 win over Houston.
Charles Woodson, CB, Green Bay (Michigan): Had seven tackles with a sack, two interceptions, returning one for a touchdown, a forced fumble and a recovered fumble in the Packers' 34-12 win over Detroit.
Anthony Spencer, DE, Dallas (Purdue): Recorded eight tackles and had two sacks in the Cowboys' 24-7 win over Oakland on Thursday.
James Laurinaitis, LB, St. Louis (Ohio State): Made nine tackles and had a sack in the Rams' 27-17 loss to Seattle.
Donte Whitner, S, Buffalo (Ohio State): Finished with 10 tackles and an interception in the Bills' 31-14 win over Miami.
Stylez White, DE, Tampa Bay (Minnesota): Recorded five tackles and had 2.5 sacks in the Buccaneers' 20-17 loss to Atlanta.
Will Smith, DE, New Orleans (Ohio State): Finished with four tackles and 1.5 sacks in the Saints' 38-17 win over New England on Monday night.
Matt Roth, LB, Cleveland (Iowa): Recorded seven tackles and a sack in the Browns' 16-7 loss to Cincinnati.
David Harris, LB, New York Jets (Michigan): Registered seven tackles and a sack in the Jets' 17-6 win over Carolina.
Julian Peterson, LB, Detroit (Michigan State): Made seven tackles with a sack and a forced fumble in the Lions' 34-12 loss to Green Bay on Thursday.
LaMarr Woodley, LB, Pittsburgh (Michigan): Finished with seven tackles and a sack in the Steelers' 20-17 loss to Baltimore on Sunday night.
Danny Clark, LB, New York Giants (Illinois): Had five tackles and a sack in the Giants' 26-6 loss to Denver on Thursday night.
Morgan Trent, CB, Cincinnati (Michigan): Recorded four tackles and had a sack in the Bengals' 16-7 win over Cleveland.
Jonathan Babineaux, DT, Atlanta (Iowa): Made three tackles with a sack and a forced fumble in the Falcons' 20-17 win over Tampa Bay.
Ray Edwards, DE, Minnesota (Purdue): Registered three tackles and a quarterback sack in the Vikings' 36-10 win over Chicago.
Chris Gamble, CB, Carolina (Ohio State): Had one tackle and an interception in the Panthers' 17-6 loss to the New York Jets.