Drew Brees, QB, New Orleans (Purdue) - Completed 33 of 48 passes for 275 yards and a touchdown in New Orleans' 16-14 win over Carolina.
Dallas Clark, TE, Indianapolis (Iowa) - Made seven catches for 68 yards and a touchdown in Indianapolis' 31-28 loss to Jacksonville.
Braylon Edwards, WR, New York Jets (Michigan) - Caught four passes for 86 yards and a touchdown in the New York Jets' 38-14 win over Buffalo.
Bradley Fletcher, CB, St. Louis (Iowa) - Recorded an interception and three tackles in St. Louis' 20-3 win over Seattle.
James Hall, DE, St. Louis (Michigan) - Made four tackles and two sacks in St. Louis' 20-3 win over Seattle.
Leon Hall, CB, Cincinnati (Michigan) - Recorded two tackles and an interception in Cincinnati's 23-20 loss to Cleveland.
A.J. Hawk, LB, Green Bay (Ohio State) - Tallied 12 tackles and an interception in Green Bay's 28-26 win over Detroit.
Chad Henne, QB, Miami (Michigan) - Completed 29 of 39 passes for 302 yards and two touchdowns in Miami's 41-14 loss to New England.
Dustin Keller, TE, New York Jets (Purdue) - Made four catches for 28 yards and two touchdowns in the New York Jets' 38-14 win over Buffalo.
Rashard Mendenhall, RB, Pittsburgh (Illinois) - Rushed for 75 yards and two touchdowns on 25 carries in Pittsburgh's 17-14 loss to Baltimore.
Rob Ninkovich, LB, New England (Purdue) - Grabbed two interceptions and recorded four tackles and a sack in New England's 41-14 win over Miami.
Kyle Orton, QB, Denver (Purdue) - Threw for 341 yards and two touchdowns on 35 of 50 passing in Denver's 26-20 win over Tennessee.
Shaun Phillips, LB, San Diego (Purdue) - Recorded four sacks, six total tackles and returned an interception for a touchdown in San Diego's 41-10 win over Arizona.
Matt Roth, LB, Cleveland (Iowa) - Made six tackles, including two sacks, in Cleveland's 23-20 win over Cincinnati.
Charles Woodson, CB, Green Bay (Michigan) - Made 13 tackles and ran an interception back for a touchdown in Green Bay's 28-26 win over Detroit.