Tom Brady, QB, New England (Michigan) - Threw for 159 yards and a touchdown on 19 of 32 passing in New England's 23-20 win over San Diego.
Alan Branch, DL, Arizona (Michigan) - Recorded five total tackles and two sacks in Arizona's 22-10 loss to Seattle.
Drew Brees, QB, New Orleans (Purdue) - Racked up 356 passing yards and two touchdowns on 37 of 56 passing in New Orleans' 30-17 loss to Cleveland.
Nate Clements, CB, San Francisco (Ohio State) - Made nine tackles and a sack in San Francisco's 23-20 loss to Carolina.
Kerry Collins, QB, Tennessee (Penn State) - Completed 17 of 31 passes for 276 yards and three touchdowns in Tennessee's 37-19 win over Philadelphia.
Lee Evans, WR, Buffalo (Wisconsin) - Caught six passes for 105 yards and three touchdowns in Buffalo's 37-34 loss to Baltimore.
Larry Foote, LB, Pittsburgh (Michigan) - Tallied four tackles and a sack in Pittsburgh's 23-22 win over Miami.
Chad Greenway, LB, Minnesota (Iowa) - Recorded 12 tackles in Minnesota's 28-24 loss to Green Bay.
A.J. Hawk, LB, Green Bay (Ohio State) - Made 11 tackles and grabbed an interception in Green Bay's 28-24 win over Minnesota.
Chad Henne, QB, Miami (Michigan) - Completed 23 of 36 passes for 257 yards and a touchdown in Miami's 23-22 loss to Pittsburgh.
Aaron Kampman, DE, Jacksonville (Iowa) - Notched five tackles and a sack in 42-20 loss to Kansas City.
Mario Manningham, WR, New York Giants (Michigan) - Caught three passes for 40 yards and a touchdown in the New York Giants' 41-35 win over Dallas.
Kyle Orton, QB, Denver (Purdue) - Threw for 198 yards and two touchdowns on 12 of 29 passing and added 21 rushing yards in Denver's 59-14 loss to Oakland.
Shaun Phillips, LB, San Diego (Purdue) - Made five tackles and a sack in San Diego's 23-20 loss to New England.
Beanie Wells, RB, Arizona (Ohio State) - Rushed for 51 yards and a touchdown on 14 carries in 22-10 loss to Seattle.
Stylez White, DE, Tampa Bay (Minnesota) - Made three tackles and a sack in Tampa Bay's 18-17 win over St. Louis.