NaVorro Bowman, LB, San Francisco (Penn State) - Racked up 15 tackles and a tackle for loss in San Francisco's 27-20 win over the New York Giants.
Tom Brady, QB, New England (Michigan) - Threw for 329 yards and three touchdowns on 26 of 39 passing in New England's 37-16 win over the New York Jets.
Drew Brees, QB, New Orleans (Purdue) - Completed 30 of 43 passes for 322 yards and two touchdowns in New Orleans' 26-23 win over Atlanta.
Kurt Coleman, S, Philadelphia (Ohio State) - Posted 11 tackles and a tackle for loss in Philadelphia's 21-17 loss to Arizona.
Chris Gamble, CB, Carolina (Ohio State) - Grabbed an interception and made a tackle in Carolina's 30-3 loss to Tennessee.
Leon Hall, CB, Cincinnati (Michigan) - Notched two tackles and an interception in Cincinnati's 24-17 loss to Pittsburgh.
Ryan Kerrigan, LB, Washington (Purdue) - Recorded six tackles and two sacks in Washington's 20-9 loss to Miami.
James Laurinaitis, LB, St. Louis (Ohio State) - Made 10 tackles and a sack in St. Louis' 13-12 win over Cleveland.
DeAndre Levy, LB, Detroit (Wisconsin) - Recorded six tackles and three tackles for loss in Detroit's 37-13 loss to Chicago.
Mario Manningham, WR, New York Giants (Michigan) - Caught six passes for 77 yards and a touchdown in the New York Giants' 27-20 loss to San Francisco.
Rashard Mendenhall, RB, Pittsburgh (Illinois) - Rushed for 44 yards and two touchdowns on 16 carries in Pittsburgh's 24-17 win over Cincinnati.
Rob Ninkovich, LB, New England (Purdue) - Recorded two interceptions, running one back for a touchdown, and added five tackles in New England's 37-16 win over the New York Jets.
Paul Posluszny, LB, Jacksonville (Penn State) - Posted six tackles, half a sack and an interception in Jacksonville's 17-3 win over Indianapolis.
Scott Shanle, LB, New Orleans (Nebraska) - Recorded nine tackles and an interception in New Orleans' 26-23 win over Atlanta.
Charles Woodson, CB, Green Bay (Michigan) - Made nine tackles, including a tackle for loss, and deflected three passes in Green Bay's 45-7 win over Minnesota.