Cliff Avril, DE, Detroit (Purdue) - Posted eight tackles, including three for loss and two sacks, along with a recovered fumble in Detroit's 34-28 win over Minnesota.
Tom Brady, QB, New England (Michigan) - Threw for 357 yards and three touchdowns on 22 of 37 passing in New England's 34-27 win over Washington.
Drew Brees, QB, New Orleans (Purdue) - Completed 36 of 47 passes for 337 yards and two touchdowns in New Orleans' 22-17 win over Tennessee.
Kurt Coleman, S, Philadelphia (Ohio State) - Made six tackles and an interception in Philadelphia's 26-10 win over Miami.
Owen Daniels, TE, Houston (Wisconsin) - Caught seven passes for 100 yards in Houston's 20-19 win over Cincinnati.
Larry Grant, LB, San Francisco (Ohio State) - Made 11 tackles in San Francisco's 21-19 loss to Arizona.
Shonn Greene, RB, New York Jets (Iowa) - Racked up 129 yards and a touchdown on 24 carries and added three catches for 58 yards in the New York Jets' 37-10 win over Kansas City.
Roy Helu, RB, Washington (Nebraska) - Rushed for 126 yards on 27 carries in Washington's 34-27 loss to New England.
Malcolm Jenkins, CB, New Orleans (Ohio State) - Made 10 tackles in New Orleans' 22-17 win over Tennessee.
James Laurinaitis, LB, St. Louis (Ohio State) - Posted 12 tackles, including one for loss, in St. Louis' 30-13 loss to Seattle.
Sean Lee, LB, Dallas (Penn State) - Made nine tackles and an interception in Dallas' 37-34 loss to the New York Giants.
Paul Posluszny, LB, Jacksonville (Penn State) - Posted seven tackles and an interception in Jacksonville's 41-14 win over Tampa Bay.
Bryan Scott, S, Buffalo (Penn State) - Made eight tackles and recovered a fumble for a touchdown in Buffalo's 37-10 loss to San Diego.
Charles Woodson, CB, Green Bay (Michigan) - Recorded six tackles and an interception in Green Bay's 46-16 win over Oakland.