Drew Brees, QB, New Orleans (Purdue) - Threw for 466 yards and three touchdowns on 33 of 43 passing in New Orleans' 45-28 win over Detroit.
Mario Manningham, WR, New York Giants (Michigan) - Caught four passes for 68 yards and a touchdown in the New York Giants' 24-2 win over Atlanta.
Tracy Porter, CB, New Orleans (Indiana) - Led the team with seven tackles in New Orleans' 45-28 win over Detroit.
Amari Spievey, S, Detroit (Iowa) - Made seven tackles in Detroit's 45-28 loss to New Orleans.
Pierre Thomas, RB, New Orleans (Illinois) - Rushed for 66 yards and a touchdown on eight carries and added six catches for 55 yards in New Orleans' 45-28 win over Detroit.
J.J. Watt, DE, Houston (Wisconsin) - Returned an interception 29 yards for a touchdown and added two tackles and a sack in Houston's 31-10 win over Cincinnati.