Tom Brady, QB, New England Patriots (Michigan) - Threw for 223 yards and one touchdown, on 23 of 31 passing, in New England's 31-21 win over Denver.
Drew Brees, QB, New Orleans Saints (Purdue) - Broke Johnny Unitas' record of 47 games with at least one touchdown pass, throwing for 370 yards and four touchdowns on 29 of 45 passing, in the Saints' 31-24 defeat of the Chargers.
Nate Clements, CB, Cincinnati Bengals (Ohio State) - Recorded nine tackles, one forced fumble and a pass deflection in the Bengals' 17-13 loss to the Dolphins.
Owen Daniels, TE, Houston Texans (Wisconsin) - Caught four passes for 79 yards and a touchdown in the Texans' 23-17 win over the Jets.
Eric Decker, WR, Denver Broncos (Minnesota) - Had four catches, including a touchdown, in the Broncos' 31-21 loss to the Patriots.
Brandon Fields, P, Miami Dolphins (Michigan State) - Averaged 49.6 yards on five punts, pinning two inside the 20-yard line, and a long of 59 yards in the Dolphins' 17-13 defeat of the Bengals.
Larry Foote, LB, Pittsburgh Steelers (Michigan) - Recorded eight tackles and two fumble recoveries in the Steelers' 16-14 win over the Eagles.
Robbie Gould, K, Chicago Bears (Penn State) - Nailed both field goal attempts and all five extra points in Chicago's 41-3 win over Jacksonville.
Chad Greenway, LB, Minnesota Vikings (Iowa) - Led Minnesota with nine tackles, including one for loss, and a pass deflection in the Vikings' 30-7 victory over the Titans.
A.J. Hawk, LB, Green Bay Packers (Ohio State) - Totaled eight tackles, including one for loss, in the Packers' 30-27 loss to the Colts.
Ryan Kerrigan, DE, Washington Redskins (Purdue) - Returned an interception 28 yards for a touchdown and added five tackles and a pass deflection in the Redskins' 24-17 loss to the Falcons.
Rashard Mendenhall, RB, Pittsburgh Steelers (Illinois) - Rushed for 81 yards and a touchdown on 14 carries and caught two passes for 20 yards in the Steelers' 16-14 win over the Eagles.
Jordan Norwood, WR, Cleveland Browns (Penn State) - Led the Browns with a career-high nine receptions for 81 yards in Cleveland's 41-27 loss to the New York Giants.
Bernard Pollard, S, Baltimore Ravens (Purdue) - Notched 10 tackles in the Ravens' 9-6 victory over the Chiefs.
Paul Posluszny, LB, Jacksonville Jaguars (Penn State) - Recorded a team-high nine tackles, including eight solo, in Jacksonville's 41-3 loss to Chicago.
J.J. Watt, DE, Houston Texans (Wisconsin) - Recorded six tackles, one sack and three pass deflections in the Texans' 23-17 wins over the Jets.
Russell Wilson, QB, Seattle Seahawks (Wisconsin) - Threw for 221 yards and a touchdown on 19 of 25 passing in the Seahawks' 16-12 defeat of the Panthers.
Tavon Wilson, FS, New England Patriots (Illinois) - Tallied 10 tackles in the Patriots' 31-21 victory over the Broncos.